Episode 53

Cancer Researcher Becomes Survivor

with Larry Coffer

What can a cancer researcher teach us when he suddenly finds himself sitting in the patient chair?

Larry Coffer spent more than 20 years at MD Anderson Cancer Center supporting ovarian and breast cancer research, helping teams develop treatments and improve patient outcomes. Long before his own diagnosis, cancer shaped his life through his stepfather’s battle with colon cancer. That experience inspired a career dedicated to helping others. Then, while training for a marathon, a routine physical revealed a rare cancer called extramedullary plasmacytoma. What began as a standard checkup quickly became a life-changing journey.

Larry shares what it was like to move from researcher to patient, receive treatment at the institution where he built his career, and navigate the uncertainty that comes with a rare diagnosis. He opens up about the emotional toll of cancer, the importance of leaning on friends, family, faith, and community, and how running helped him process the experience. He also discusses his work as a stem cell donor and advocate, helping others understand the life-saving impact of bone marrow and stem cell donation.

Larry’s story is a reminder that a diagnosis does not define who you are. With support, purpose, and hope, it is possible to keep moving forward one step at a time.

Highlights:

1. How a routine health screening uncovered a rare cancer with no warning signs

2. What changes when a cancer researcher becomes a cancer patient

3. Why support systems matter even for the people who seem strongest

4. How running, faith, and community can help during treatment and recovery

5. What stem cell donation really involves and why more donors are urgently needed

Mentioned Resources:

CanCare- www.cancare.org

Larry’s Marathon Fundraiser for CanCare - https://fundraisers.hakuapp.com/larry-coffer

About the Guest:

Larry Coffer is a plasma cell cancer survivor, cancer researcher, stem cell donor, and marathon runner. For more than 20 years, he has led groundbreaking research at MD Anderson Cancer Center focused on ovarian and breast cancer. Then a routine physical before a marathon changed everything. Larry completed 20 rounds of radiation and rang the bell in January 2026. His running community has a special connection to CanCare, a full-circle moment. Larry shares what happens when the science becomes personal, and what he found on the other side.

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